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Xx male syndrome, also known as de la chapelle syndrome or 46,xx testicular disorder of sex development (or 46,xx dsd) is a rare intersex condition in which an individual with a 46,xx karyotype develops a male phenotype [2] in 90 percent of these individuals, the syndrome is caused by the y chromosome's sry gene, which triggers male reproductive. [2][3][4][5][6] in 90 percent of these individuals, the syndrome is caused by the father's y chromosome 's sry gene, being atypically included in the crossing over of genetic.
Understanding xx male syndrome xx male syndrome, also known as de la chapelle syndrome, is a condition where an individual has two x chromosomes, which are typically associated with female genetic sex, but exhibits male external genitalia and internal reproductive structures. Rare congenital condition xx male syndrome, also known as de la chapelle syndrome, is a rare congenital intersex condition where an individual with a 46 xx karyotype (otherwise associated with females) has phenotypically male characteristics that can vary among cases In human biology, the typical understanding of sex determination is that biological men have xy chromosomes, while biological women have xx chromosomes.
A rare disorder where individuals with two x chromosomes develop male characteristics due to sry gene translocation.
Xx male syndromedefinitionxx male syndrome occurs when the affected individual appears as a normal male, but has female chromosomes Two types of xx male syndrome can occur Those with detectable sry gene and those without detectable sry (sex determining region y) Sry is the main genetic switch for determining that a developing embryo will become male
Source for information on xx male. Xx males is defined as a condition characterized by testicular development and complete virilization of the genitalia in individuals with two x chromosomes and no y chromosome, resulting in male phenotypes despite the absence of y chromosome genes involved in spermatogenesis This condition is often diagnosed in puberty or adulthood due to associated features such as small testes, gynecomastia. What is the prognosis of xx male syndrome
With hormonal replacement, therapy, surgery and multidisciplinary follow up the prognosis of xx male syndrome is good
The patients can live a fairly normal life but like all disorders, they require a strong social support system, in the presence of which the quality of life is greatly improved. (1) xx males with normal external or internal genitalia (2) xx males with ambiguity, usually detected at birth by external genital ambiguities such as. A syndrome characterized by the presence of an xx sex chromosome complement in an individual with male genitalia including both testes but no sperm production (azoospermia).
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