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Leak channels, also referred to as leakage or passive channels, represent the most basic type of ion channel found in cells, essential for shaping the membrane's potential difference For calculations of resting state neuronal potential, we assume that all gated channels are closed. This perpetual openness enables ions to move across the membrane according to their respective.
Your prof might have thought you meant gated ion channels, which open and close under certain conditions Gated channels can thus transiently change the permeability to an ion i.e only when a ligand is bound Leak channels are always open to allow ions to enter/exit the cell
For example potassium ion leak channels allow k+ ions to slowly leave the cell
A gated ion channel only opens when something activates it For example, a voltage gated ion channel only opens when the voltage of the. A) a depolarizing stimulus b) an inhibitory stimulus c) a temporal stimulus d) an. Understanding leak channels leak channels are specialized protein structures embedded within cellular membranes
They play a crucial role in maintaining the cell’s ionic balance and overall homeostasis Unlike gated channels, which open and close in response to specific stimuli, leak channels allow ions to flow freely across the membrane. These channels have narrow, highly selective pores lined by conserved amino acid residues that allow the diffusion of only specific ions. Remember, leak channels are always open, but gated channels open in response to a stimulus
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